When standard antidepressants haven't worked, Spravato offers a fundamentally different approach. It's an FDA-approved nasal-spray treatment for treatment-resistant depression, given right here in our office under careful medical supervision.
Spravato (esketamine) works differently from traditional antidepressants. Instead of acting on serotonin like most pills, it targets a different pathway in the brain — and for many people with treatment-resistant depression, that difference is exactly why it can help when other medications haven't.
It's delivered as a nasal spray that you self-administer in our office, under the supervision of our clinical team. Because it works through a new mechanism, Spravato is approved specifically for adults whose depression hasn't responded to other treatments, and for depressive symptoms in adults with major depressive disorder who have suicidal thoughts or actions.
Spravato is considered when depression has proven difficult to treat. You may be a candidate if:
Spravato is used together with an oral antidepressant, and whether it's right for you is always decided through a careful evaluation with your clinician.
We review your history and prior treatments to confirm Spravato is appropriate and safe for you.
You take the nasal spray yourself, in our calm treatment space, guided by our team.
Because of how Spravato works, you'll be monitored for about two hours after each dose to make sure you're safe and comfortable.
You won't be able to drive after treatment, so you'll arrange for someone to take you home and rest for the remainder of the day.
Treatment typically starts with sessions a couple of times per week, then spaces out over time based on your response.
Both are powerful tools for treatment-resistant depression. The right choice depends on your situation, and we'll help you decide.
A medication-based nasal spray taken in-office with monitoring. Often works quickly and suits patients open to a medication approach with a different mechanism.
A drug-free, non-invasive treatment using magnetic pulses. No sedation, no ride needed, and you return to your day right after. Also FDA-cleared for OCD.
Spravato is provided through a certified program that requires in-office administration and monitoring for safety. You can't take it at home.
Spravato can cause temporary drowsiness, dizziness, or changes in perception, so you'll need someone to drive you home and should not drive until the next day after a full night's sleep.
Some patients notice improvement relatively quickly, but responses vary. We'll track your progress closely and adjust your plan together.
Many insurers cover Spravato for treatment-resistant depression when criteria are met. We can help you understand your coverage, and self-pay options are available.
If your depression has resisted treatment, Spravato may offer the relief you've been searching for. Let's talk it through and check your eligibility.
Request a consultationSpravato® is a registered trademark of its respective owner. Spravato is available only through a restricted program under a REMS and must be administered under direct medical supervision. It carries important risks, including sedation, dissociation, and potential for abuse — your clinician will review all benefits and risks with you. This page is for general educational purposes and is not medical advice. Individual results are not guaranteed and may vary from person to person.